The report  «Problems and Prospects of Russia's Cooperation with US / NATO in the Field of Missile Defense» was prepared under the auspices of Euro-Atlantic Security Initiative (EASI). The EASI project was launched by the Carnegie Endowment for International Реace and is implemented Ьy а group of prominent politicians and experts from Russia, the USA and Europe aiming to elaborate proposals оп the new Euro-Atlantic security space. The Institute of World Еconоmy and International Relations is the key partner of the project in Russia. The study covers оnе of the most significant military and political issues of relations between Russia and the US/NATO - the prospects for missile defense (MD) cooperation. The group of authors includes defense professionals, specialists in national and international security and international politics from the Institute and other organizations. The authors review various aspects of Russian and US/ NATO approaches towards building and possible integration of MD systems, as well as identifying and analyzing the basic political and certain military-technical contradictions, and other obstacles to cooperation. Supplements include illustrative materials provided by the Russian Defense Ministry.