Abstract. The Editorial Board publishes a brief report on the round table at the Center for Asia Pacific Studies of IMEMO on new phenomena in the system of international relations in the Indo-Pacific Region (IPR) and in the policies of the states located there. The sharp increase in the level of confrontation in different regions of the world over the past year leads to increased importance in the system of international relations, in the foreign policy of states of such categories as “friendliness” and “unfriendliness” in relation to other countries. These phenomena have also affected the Indo-Pacific region, which now plays a key role in world politics and economy, where complicated and sometimes multidirectional processes of restructuring the political space, reformatting economic, military and political relations between states are taking place. In this context, it seems relevant to analyze the influence of the factors of “friendship/unfriendliness” on the formation of the main “axes” of rapprochement and confrontation in the region, new blocs and coalitions. The determination of Russia’s new positioning in the IPR taking into account the factors mentioned above also becomes an important independent research task. These and other closely related issues were the object of discussion at the round table held by the Center for Asia Pacific Studies of IMEMO in late October 2022. At the same time the discussion participants focused on the analysis of policies not of all countries in the region, but mainly of the Pacific Asia (PA) and India and South Asia. The panelists were K.R. Voda, Cand. Sci. (Polit.), Scientific Secretary of IMEMO; L.A. Gamza, senior researcher at IMEMO; O.V. Davydov, retired Ambassador-at-Large, senior researcher at IMEMO; E.A. Kanaev, Dr. Sci. (Hist.), Professor at National Research University Higher School of Economics; A.N. Karneev, Cand. Sci. (Hist.), Professor at National Research University Higher School of Economics; A.V. Kupriyanov, Cand. Sci. (Hist.), Head of the Group at IMEMO; V.L. Larin, RAS Academician, Deputy Chairman of the Presidium of FEB RAS; A.V. Lomanov, Dr. Sci. (Hist.), Professor of RAS, Deputy Director of IMEMO; S.A. Lukonin, Cand. Sci. (Econ.), Head of the Sector, IMEMO; V.V. Mikheev, RAS Academician, Member of the IMEMO Directorate; V.V. Sumskiy, Dr. Sci. (Hist.), principle researcher at IMEMO; M.A. Terskikh, Cand. Sci. (Polit.), researcher at IMEMO; V.G. Shvydko, Cand. Sci. (Econ.), Head of the Group at IMEMO.