Abstract. The Taliban’s (terrorist organization banned in Russia) victory in Afghanistan creates new threats and challenges to the countries of Central Asia. At the same time, the attitude of the Central Asian republics to the new government is significantly different. While Tajikistan is not yet ready to establish ties with the Taliban, Uzbekistan, interested in economic projects with Afghanistan, aims to develop good-neighborly relations with the Taliban. In the context of the aggravation of the situation on the southern borders of the CIS, cooperation between Russia and the countries of the region in the field of security is strengthening, which increases its role in Central Asia. Having carried out the withdrawal of its troops from Afghanistan, the United States does not abandon its attempts to gain a foothold in the region, seeking to involve the Central Asian countries in solving their problems. At the same time, proposals are being put forward that may create additional difficulties for the Central Asian republics.