The article analyzes the US foreign policy in the Middle East in the context of the growing confrontation between the collective West and Russia against the backdrop of the Ukrainian crisis. Particular attention is paid to the results of the visit of US President Joe Biden to Israel, to the West Bank of the Jordan River to the State of Palestine and to Saudi Arabia, which he made in mid-July 2022. The author comes to the conclusion that another attempt by Washington to draw the countries of the region into its behind-the-scenes foreign policy games has failed. The Middle Eastern allies and partners of the United States represented by Israel, the monarchies of the Persian Gulf and other Arab states took a neutral position in relation to the confl ict in Ukraine, and the oil and gas exporting countries did not go for a sharp increase in hydrocarbon supplies to the EU countries and the UK, as he insistently asked Biden. The White House failed to put together a regional anti-Iranian bloc on the basis of the Cooperation Council for the Arab States of the Persian Gulf (GCC), as the leaders of Qatar, Oman and Iraq are determined to maintain their traditional ties and contacts with Tehran. Moreover, these countries are making mediation eff orts to normalize relations between the Saudi Arabia and Iran, and there are prerequisites for success in this matter. In general, the Arabs do not support the US administration's concept of hegemony in the world and building a unipolar world order in the Middle East. Even with some remaining dependence on the United States and the West as a whole in the fi nancial, economic, military-technical and other fi elds, the Arab countries prefer to pursue an independent policy on key issues of our time, develop a multipolar world, and maintain mutually benefi cial and respectful relations with all states, including China and Russia. The Arab capitals are in no hurry to speed up the rapprochement with the State of Israel, which is imposed by Washington, expecting from its leadership to intensify eff orts to justly resolve the Palestinian problem and liberate the illegally occupied Arab lands. Even the bogey exaggerated by the White House of a common threat to the Middle East from the hypothetical appearance of Iran's nuclear weapons and its expansion in the region cannot persuade the Persian Gulf monarchies and other Arab countries to cooperate with Jerusalem in the military or military-technical fi elds.